Ghana, a lower-middle-income country, was the first country to sign a Global Fund grant in late 2002. The country faces significant challenges from malaria, HIV and tuberculosis. Malaria accounts for 8% of deaths in the country. Ghana is also one of the countries with the highest burden of multidrug-resistant tuberculosis (MDR-TB) in the world. A recent survey showed that TB prevalence had been underestimated at 71 per 100,000, establishing that the prevalence is now estimated at 264 per 100,000 – a more than 300% difference. The Global Fund considers Ghana as one of the 20 high "impact countries" worldwide that

  • account for 70% of the worldwide burden of HIV/AIDS, tuberculosis and malaria and
  • receive 70% of the value of the Global Fund grants.

In response, Ghana is making robust commits to increase its domestic investments in health. Working with the Global Fund partnership, Ghana has distributed 19 million mosquito nets, and lowered the death rate among children under five due to malaria from 14% in 2000 to less than 1% in 2012. The country has registered a 43% decrease of new HIV infections since 2010, and increased coverage of prevention of mother-to-child transmission coverage from 32% to 81%. Over 76,000 new tuberculosis cases have been detected and treated.

To date (December 2017), the Global Fund has invested in Ghana as follows:

Component Signed Committed Disbursed
HIV/AIDS US$333,968,297 US$331,557,890 US$322,895,631
Tuberculosis US$89,449,430 US$85,895,647 US$83,595,546
Malaria US$347,848,675 US$344,739,803 US$338,836,459
Total US$771,266,402 US$762,193,340 US$745,327,636


In 2015, Ghana signed grants amounting to 254 million USD that are made up as follows: